A REVIEW OF SODIUM PENTOBARBITAL (NAP)

pentobarbital will lessen the extent or effect of oliceridine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. If coadministration with a CYP3A4 inducer is important, consider raising oliceridine dose until secure drug effects are obtained; watch for signs of opioid withdrawal.pentobarbital will decrease the ext